NNMTi yog dab tsi?
Feem ntau NAD⁺- tsom cov khoom lag luam vam khom ncaj qha ua ntej ntxiv (xws li NMN lossis NR). Thaum cov txheej txheem no txhawm rau txhawm rau nce NAD⁺ muaj los ntawm kev muab cov tsev thaiv ntxiv, lawv tsis hais txog cov txheej txheem metabolic uas tuaj yeem txwv NAD⁺efficiency-tshwj xeeb hauv cov ntaub so ntswg laus.
NNMTi muab cov tswv yim ntxiv thiab kev sib txawv ntawm kev siv tshuab los ntawm kev tsom cov enzyme uas tswj kev siv nicotinamide (NAM) hauv NAD⁺salvage txoj kev.
|
Feature |
NNMTi |
NAD⁺ Precursors (NMN / NR) |
|
Thawj mechanism |
Tswj NNMT kev ua ub no kom khaws NAM muaj |
Khoom siv exogenous NAD⁺ tsev blocks |
|
Txoj hauj lwm hauv txoj kev |
Upstream metabolic modulation |
Lub substrate supplementation |
|
Impact on NAM |
Txwv tsis pub dhau NAM methylation |
Tsis tswj NAM noj |
|
NAD⁺ pathway efficiency |
Txhawb endogenous recycling tshuav nyiaj li cas |
Nyob ntawm lub peev xwm hloov cellular |
|
Qhov cuam tshuam rau cov leeg laus |
Chaw nyob hnub nyoog -txog NNMT overexpression |
Tej zaum yuav raug cuam tshuam los ntawm hnub nyoog - cuam tshuam txog kev cuam tshuam ntawm metabolic |
|
Formulation tswv yim |
Kev tswj hwm & txhawb nqa |
Ntxiv / hloov |
Vim li cas qhov no?
Raws li NNMT kev nthuav qhia nce nrog cov leeg pob txha laus, ntau tshaj methylation ntawm NAM tuaj yeem txo cov pas dej ntawm NAD.+ precursors thiab cuam tshuam cellular zog metabolism. Tsuas yog ntxiv cov precursors ntau yuav tsis them nyiaj rau qhov tsis txaus ntseeg no.
NNMTi tsom mus rau optimizing lub cev tus kheej NAD+ Txoj kev khaws cia, pab tswj cov metabolism hauv kev ua haujlwm zoo dua li tsis cuam tshuam cov kab ke nrog cov substrates ntxiv.
- Strategic Advantages for Formulation
- Complements NAD+cov khoom xyaw ua ntej
- Txhawb nqa metabolic tshuav thiab cellular zog homeostasis
- Tshwj xeeb yog cuam tshuam rau kev noj qab haus huv laus thiab cov leeg nqaij vitality formulations
- Kev sib txawv ntawm cov txheej txheem rau tom ntej - tiam NAD+ kev txhawb nqa
NNMTi yog npaj rau kev siv nutraceutical thiab kev noj qab haus huv. Nws tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
Daim ntawv pov thawj ntawm Kev Ntsuam Xyuas:
NNMTi cov yam ntxwv yog dab tsi?
High Purity - NNMTi yog tsim los siv cov txheej txheem tsim ua kom zoo kom ua tiav siab purity, uas ua kom zoo dua bioavailability.
Targeted Action - NNMTi tshwj xeeb yog lub hom phiaj ntawm NNMT enzyme, inhibiting nws cov dej num thiab modulating nicotinamide metabolic txoj kev.
Stability - NNMTi qhia tau tias muaj kev ruaj ntseg zoo heev, tswj nws cov haujlwm thiab ua haujlwm tau zoo nyob rau hauv ntau yam ib puag ncig thiab kev cia khoom.
Kev Txhim Kho Muaj Peev Xwm - Ua tsaug rau nws cov khoom tshwj xeeb, NNMTi tau nyiam cov neeg nyiam thiab tuav cov kev cia siab dav rau kev tshawb fawb thiab
Dab tsi yog Mechanism Of Action ntawm NNMTi?
5-Amino-1MQ ua haujlwm feem ntau ua tus inhibitor ntawmNNMT (Nicotinamide N{0}}methyltransferase), ib qho tseem ceeb regulator ntawm cellular metabolism.
Los ntawm inhibiting NNMT, nws yuav:
Nce intracellularNAD + qib
Txhim kholub zog metabolism efficiency
Txo cov rog cov cim qhia
Txhim kho metabolic yooj
Cov txheej txheem no ua haujlwm 5-Amino-1MQ raws li kev cog lus cog lus hauvKev tshawb fawb txog kev noj qab haus huv metabolic thiab tswj qhov hnyav.
5-Amino-1MQ ua haujlwm li cas?
NNMTi yog ib qho muaj zog thiab xaiv nicotinamide N-methyltransferase (NNMT) inhibitor nrog IC50ntawm 1.2 μM, tsim los hloov kho NNMT kev ua haujlwm ntawm substrate-binding site. NNMT ua lub luag haujlwm tseem ceeb hauv cellular metabolism thiab NAD⁺ txoj kev tswj hwm, tshwj xeeb tshaj yog nyob rau hauv cov leeg pob txha.
Cov kev tshawb fawb preclinical qhia tau hais tias NNMTi txhawb nqa kev sib txawv ntawm myoblast, txhim kho cov leeg leeg hlwb, thiab cuam tshuam nrog kev txhim kho cov leeg nqaij, lub cev muaj pes tsawg leeg, thiab kev sib npaug ntawm metabolic. NNMTi yog qhov zoo rau kev tsim cov hom phiaj kev laus noj qab haus huv, cov leeg muaj zog, thiab NAD+txhawb nqa metabolism.
Rau kev tshawb fawb thiab kev siv nutraceutical nkaus xwb.
Hauv cov ntaub ntawv tshawb fawb, 5-Amino-1MQ tau siv los ua qhov kev tshawb fawb tshawb fawb los tshawb xyuas NNMT-txuas nrog txoj hauv kev metabolic thiab cov lus teb hauv qab ntawm tes hauv cov qauv tsis kho mob.
- NNMT-txoj kev kho nicotinamide methylation
- NAD+- koom nrog kev tswj hwm metabolic
- Kev siv hluav taws xob ntawm tes thiab kev ua kom lub cev muaj zog
- GLUT4-txuas ntxiv cov piam thaj thauj khoom (kev sim ntsiab lus)
- Stem cell-txog cov cim kev hloov pauv hauv cov qauv qauv
Txhua daim ntawv thov tseem txwv rau qhov chaw soj ntsuam kev tshawb fawb ib puag ncig.
Peb cov qauv OEM ntawm 5-Amino-1MQ capsules rau koj siv.
MATERIAL NYIAJ rau ib lub kaus mom
5-Amino-1MQ Capsule 50 mg
Lwm cov khoom xyaw Gelatin (capsule plhaub), Microcrystalline Cellulose, Magnesium Stearate, Silica.
OEM formula activates:
*nicotinamide N-methyltransferase
* NAD + Activator
* NNMT Inhibitor
* Customized capsule plhaub (loj, xim, khoom)
* kev cai lable (PVC, Synthetic ntawv)
* Customized ntau npaum (20mg, 50mg)
* lub raj mis customized (loj, xim, khoom siv)
Capsule loj rau koj siv
Test rau 5-Amino-1MQ:
FAQ:
Peb qhov kev txiav txim yam tsawg kawg nkaus yog dab tsi?
Npaj-rau- nkoj: 500–1,000 units (khoom-nyob ntawm).
Kev cai (packaging/formula): 3,000+ units (negotiable).
Me -batch custom: 100+ units (20–30% tus nqi hwm).
Peb tus nqi rau OEM yog dab tsi?
Tus nqi ntawm lub vev xaib tsuas yog siv rau kev siv xwb. Qhov kawg quotes nyob ntawm qhov kev txiav txim ntim, customization, thiab cov nqe lus them nqi.
Kev txo nqi ntau: 3-15% rau kev txiav txim siab tshaj 10,000 units.
5-Amino-1MQ siv rau dab tsi?
Nws tau kawm dav rau nws lub luag haujlwm muaj peev xwm hauvtxo cov rog, txhim kho metabolic, thiab tswj lub zog ntawm tes.
Yuav ua li cas yog nws txawv ntawm ib txwm poob phaus ntxiv?
Tsis zoo li stimulants, 5-Amino-1MQ lub hom phiajCellular metabolism txoj kev (NNMT)es tsis qab los noj mov.
Cov khoom no puas haum rau kev siv txhua hnub?
Kev siv nyob ntawm tus kheej raws tu qauv; kev cob qhia kws tshaj lij raug pom zoo.
Yuav tsum khaws cia li cas?
Khw hauv atxias, qhuav qhov chaw deb ntawm lub teeb thiab noo noo.
Peb txoj cai qauv yog dab tsi?
Cov khoom txheem: Dawb (cov neeg siv khoom them tus nqi thauj khoom).
Cov qauv kev cai: Them tus nqi (txiav tawm los ntawm kev txiav txim ntau).
Peb cov lus qhia tseem ceeb yog dab tsi?
"Made in USA" Labeling: Cov khoom tsim nyob rau hauv Suav teb. "MADE IN USA" daim ntawv lo tsis ua raws li -.
Yuav ua li cas txog peb tus nqi sib txawv?
Cov nqi muag khoom hauv online; lag luam wholesale quotes raws li kev txiav txim ntim.
Peb cov ntawv tseem ceeb yog dab tsi?
EU / US Muag: Txhua yam khoom ua raws li cov cai hauv zos. Paub meej tias lub tebchaws yuav tsum tau ua ua ntej.
Custom Orders: Cia 7-10 hnub ntxiv rau kev tsim qauv / qauv (nrog rau tag nrho lub sijhawm ua haujlwm).
Cov khoom me me: MOQ 100 units (tus nqi siab dua + tus nqi tsim qauv).
Yog xav yuav5-Amino-1MQcapsules, pls xav tiv tauj Xi'an Ruichi Biotech Co., Ltd.
Tsim los rau hauv daim ntawv yooj yim capsule, cov khoom no ua kom ntseeg taukev noj tshuaj kom raug, txhim kho kev nqus, thiab siv tau yooj yim, ua rau nws zoo tagnrho rau niaj hnub metabolic txhawb raws tu qauv.
E-mail:Jenny@ruichibio.com
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